کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2195646 1098743 2015 20 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Do intermittent diets provide physiological benefits over continuous diets for weight loss? A systematic review of clinical trials
ترجمه فارسی عنوان
آیا رژیم های متناوب فوایدی برای رژیم های مداوم برای کاهش وزن ارائه می دهند؟ بررسی سیستماتیک آزمایشات بالینی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
چکیده انگلیسی


• Energy restriction induces adaptive physiological responses that hinder weight/fat loss.
• Intermittent energy balance periods might reduce adaptive responses during energy restriction.
• Intermittent fasting reduces body weight and possibly appetite but not other adaptive responses.
• Intermittent fasting is an equivalent alternative to continuous energy restriction for weight loss.

Energy restriction induces physiological effects that hinder further weight loss. Thus, deliberate periods of energy balance during weight loss interventions may attenuate these adaptive responses to energy restriction and thereby increase the efficiency of weight loss (i.e. the amount of weight or fat lost per unit of energy deficit). To address this possibility, we systematically searched MEDLINE, PreMEDLINE, PubMed and Cinahl and reviewed adaptive responses to energy restriction in 40 publications involving humans of any age or body mass index that had undergone a diet involving intermittent energy restriction, 12 with direct comparison to continuous energy restriction. Included publications needed to measure one or more of body weight, body mass index, or body composition before and at the end of energy restriction. 31 of the 40 publications involved ‘intermittent fasting’ of 1–7-day periods of severe energy restriction. While intermittent fasting appears to produce similar effects to continuous energy restriction to reduce body weight, fat mass, fat-free mass and improve glucose homeostasis, and may reduce appetite, it does not appear to attenuate other adaptive responses to energy restriction or improve weight loss efficiency, albeit most of the reviewed publications were not powered to assess these outcomes. Intermittent fasting thus represents a valid – albeit apparently not superior – option to continuous energy restriction for weight loss.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular and Cellular Endocrinology - Volume 418, Part 2, 15 December 2015, Pages 153–172
نویسندگان
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