کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2202363 1551336 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Increased production of autoantibodies and specific antibodies in response to influenza virus vaccination in physically active older individuals
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Increased production of autoantibodies and specific antibodies in response to influenza virus vaccination in physically active older individuals
چکیده انگلیسی

Immunosenescence is associated to aging and among many changes in immune response is reported a reduced response to vaccination and an increase in the number of cases of autoimmunity, caused by autoantibodies known as natural antibodies whose function, according to reports, would be protection against infection and inflammation. Although immunosenescence is an irreversible process, regular moderate exercise can attenuate some aspects of the decline in the immune system. So, the aim of this study was to investigate the humoral immune response in physically active elderly individuals before and 30 days after vaccination against influenza virus. The results showed that the percentage of individuals positive for antinuclear antibodies and serum immunoglobulin M and G levels after vaccination were higher in the group that exercised regularly than in the sedentary group. We were also able to demonstrate a significant correlation between levels of natural autoantibodies and response to vaccination.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Results in Immunology - Volume 3, 2013, Pages 10–16
نویسندگان
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