کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2203011 1551400 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Plant responses against invasive nucleic acids: RNA silencing and its suppression by plant viral pathogens
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Plant responses against invasive nucleic acids: RNA silencing and its suppression by plant viral pathogens
چکیده انگلیسی

RNA silencing is a common strategy shared by eukaryotic organisms to regulate gene expression, and also operates as a defense mechanism against invasive nucleic acids such as viral transcripts. The silencing pathway is quite sophisticated in higher eukaryotes but the distinct steps and nature of effector complexes vary between and even within species. To counteract this defense mechanism viruses have evolved the ability to encode proteins that suppress silencing to protect their genomes from degradation. This review focuses on our current understanding of how individual components of the plant RNA silencing mechanism are directed against viruses, and how in turn virus-encoded suppressors target one or more key events in the silencing cascade.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cell & Developmental Biology - Volume 20, Issue 9, December 2009, Pages 1032–1040
نویسندگان
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