کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2203189 1100423 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Xenopus as a model system for vertebrate heart development
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Xenopus as a model system for vertebrate heart development
چکیده انگلیسی

The African clawed frog, Xenopus laevis, is a valuable model system for studies of vertebrate heart development. In the following review, we describe a range of embryological and molecular methodologies that are used in Xenopus research and discuss key discoveries relating to heart development that have been made using this model system. We also discuss how the sequence of the Xenopus tropicalis genome provides a valuable tool for identification of orthologous genes and for identification of evolutionarily conserved promoter elements. Finally, both forward and reverse genetic approaches are currently being applied to Xenopus for the study of vertebrate heart development.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cell & Developmental Biology - Volume 18, Issue 1, February 2007, Pages 46–53
نویسندگان
, ,