کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2203322 1100437 2006 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development of Drosophila motoneurons: Specification and morphology
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Development of Drosophila motoneurons: Specification and morphology
چکیده انگلیسی

In the Drosophila ventral nerve cord, segmentally repeated sets of ∼80 motoneurons are generated during embryogenesis. Within each hemisegment, each motoneuron is characterised by its axonal projection and innervation of a particular target muscle as well as its dendritic tree in the central nervous system. Codes of transcriptional regulators appear to specify in a hierarchical fashion the cell type, motoneuron sub-types and eventually unique cellular identities. Recent studies show that patterns of connectivity in the periphery are mirrored by patterns of dendritic arborisation centrally thereby providing a neuronal correlate of connectivity to the anatomy of the motor system in the periphery. While the principal mechanisms that underlie the development of the peripheral neuromuscular system have been studied in some detail, much less is known about how the dendrites and their patterns of connections develop in the CNS.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cell & Developmental Biology - Volume 17, Issue 1, February 2006, Pages 3–11
نویسندگان
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