کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2204745 1100816 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regulation and control of myosin-I by the motor and light chain-binding domains
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Regulation and control of myosin-I by the motor and light chain-binding domains
چکیده انگلیسی

Members of the myosin-I family of molecular motors are expressed in many eukaryotes, where they are involved in a multitude of critical processes. Humans express eight distinct members of the myosin-I family, making it the second largest family of myosins expressed in humans. Despite the high degree of sequence conservation in the motor and light chain-binding domains (LCBDs) of these myosins, recent studies have revealed surprising diversity of function and regulation arising from isoform-specific differences in these domains. Here we review the regulation of myosin-I function and localization by the motor and LCBDs.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 23, Issue 2, February 2013, Pages 81–89
نویسندگان
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