کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2204929 1100843 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regulation of actin cytoskeleton dynamics by Arf-family GTPases
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Regulation of actin cytoskeleton dynamics by Arf-family GTPases
چکیده انگلیسی

Small GTPases of the Arf family are best known for their role in vesicular transport, wherein they nucleate the assembly of coat proteins at sites of carrier vesicle formation. However, accumulating evidence indicates that the Arfs are also important regulators of actin cytoskeleton dynamics and are involved in a variety of actin-based processes, including cell adhesion, migration and neurite outgrowth. The mechanisms of this regulation are remarkably diverse, ranging from the integration of vesicular transport with cytoskeleton assembly to the direct regulation of Rho-family GTPase function. Here, we review recent progress in our understanding of how Arfs and their interacting proteins function to integrate membrane and cytoskeletal dynamics.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 18, Issue 4, April 2008, Pages 184–192
نویسندگان
, ,