کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2204979 | 1100848 | 2008 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Ustilago maydis, a new fungal model system for cell biology Ustilago maydis, a new fungal model system for cell biology](/preview/png/2204979.png)
The use of fungal model systems, such as Saccharomyces cerevisisae and Schizosaccharomyces pombe, has contributed enormously to our understanding of essential cellular processes in animals. Here, we introduce the corn smut fungus Ustilago maydis as a new model organism for studying cell biological processes. Genome-wide analysis demonstrates that U. maydis is more closely related to humans than to budding yeast, and numerous proteins are shared only by U. maydis and Homo sapiens. Growing evidence suggests that basic principles of long-distance transport, mitosis and motor-based microtubule organization are conserved between U. maydis and humans. The fungus U. maydis, therefore, offers a unique system for the study of certain mammalian processes.
Journal: - Volume 18, Issue 2, February 2008, Pages 61–67