کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2204993 1100850 2009 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Merlin and the ERM proteins – regulators of receptor distribution and signaling at the cell cortex
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Merlin and the ERM proteins – regulators of receptor distribution and signaling at the cell cortex
چکیده انگلیسی

Recent studies highlight the importance of the distribution of membrane receptors in controlling receptor output and in contributing to complex biological processes. The cortical cytoskeleton is known to affect membrane protein distribution but the molecular basis of this is largely unknown. Here, we discuss the functions of Merlin and the ERM proteins both in linking membrane proteins to the underlying cortical cytoskeleton and in controlling the distribution of and signaling from membrane receptors. We also propose a model that could account for the intricacies of Merlin function across model organisms.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 19, Issue 5, May 2009, Pages 198–206
نویسندگان
, ,