کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2205120 1100863 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reproduction and longevity: secrets revealed by C. elegans
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Reproduction and longevity: secrets revealed by C. elegans
چکیده انگلیسی

What is the relationship between reproduction and longevity? Evolutionary biology suggests that reproduction exacts a cost in somatic maintenance, a cost that reduces longevity. The frequent occurrence of this tradeoff between life span and fecundity, both due to experimental manipulations as well as natural variation, suggest that the mechanism might be conserved during evolution. Until recently, little was known about the mechanistic details of how reproduction might regulate life span. Here we discuss recent advances in our understanding of the regulation of life span by reproductive signaling, focusing on studies using Caenorhabditis elegans.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 17, Issue 2, February 2007, Pages 65–71
نویسندگان
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