کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
227433 | 464822 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electro-oxidation and determination of gemcitabine hydrochloride, an anticancer drug at gold electrode
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Electrochemical behavior of an anticancer drug, gemcitabine hydrochloride (GMB) was studied in 10.4 pH with 0.2 M phosphate buffer solution as supporting electrolyte at 25 ± 0.1 °C at gold electrode (GE) using different voltammetric techniques. The electrochemical process was observed to be diffusion controlled, irreversible and involving one-electron oxidation. Under optimal conditions, the peak current was proportional to GMB concentration in the range of 0.1–15 μM with a detection limit of 0.06 μM by differential pulse voltammetry. The method was developed for the determination of GMB in pharmaceutical formulations and urine as a real sample.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Industrial and Engineering Chemistry - Volume 19, Issue 6, 25 November 2013, Pages 1933–1938
Journal: Journal of Industrial and Engineering Chemistry - Volume 19, Issue 6, 25 November 2013, Pages 1933–1938
نویسندگان
Keerti M. Naik, Sharanappa T. Nandibewoor,