کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
230917 1427413 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Statistical mixture design investigation of CO2–Ethanol–H2O pressurized solvent extractions from tara seed coat
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Statistical mixture design investigation of CO2–Ethanol–H2O pressurized solvent extractions from tara seed coat
چکیده انگلیسی

Tara (Caesalpinia spinosa) fruit seed coat is an abundant Peruvian agro-industrial residue that could be explored as a raw material for the production of valuable phenolic- and antioxidant-rich extracts. In this work, a mixture design was applied to optimize solvent mixtures for selective extraction of phenolic compounds from tara fruit seed coat. Pressurized solvent extractions (PSE) were performed at 313 K and 20 MPa, using homogeneous CO2, ethanol (EtOH) and H2O solvent mixtures. Extraction kinetics was obtained and phenolic contents, antioxidant activities (measured by the coupled oxidation of β-carotene and linoleic acid) and anti-inflammatory activities (measured by the lipoxygenase inhibition activity) of extracts were evaluated. A linear mixture model predicted total yields and it was verified that H2O was the most effective solvent to obtain high extraction yields. A quadratic model predicted extracts’ phenolic contents and it was verified that H2O and CO2 had an antagonistic effect and that maximum phenolic contents can be expected for EtOH-rich mixtures. A special cubic model predicted anti-inflammatory activities and the maximum activities were also predicted for EtOH-rich mixtures. For the antioxidant activity, no model revealed to be significant (at a 95% confidence level). Nevertheless, high antioxidant activities were observed after 3 h of assay (above 80% of oxidation inhibition for nine out of eleven extracts) and even after 6 h of assay (above 70%). The obtained results strongly suggest that tara seed coat is a residue that has great potential to be valorized for the production of phenolic-rich extracts presenting high anti-inflammatory and antioxidant activities.

Figure optionsDownload as PowerPoint slideHighlights
► Tara seed coat.
► High pressure extraction using homogeneous CO2, ethanol and H2O mixtures.
► Statistical mixture design was applied to optimize solvent mixture.
► A linear, a quadratic and a special cubic model predicted total yields, phenolic contents and anti-inflammatory activities, respectively.
► The obtained results strongly suggest that tara seed coat is a residue that has great potential to be valorized.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Supercritical Fluids - Volume 64, April 2012, Pages 9–18
نویسندگان
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