کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
239733 | 466199 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Impact of flow-through regime on the cultivation of epithelial cells on quartz crystal resonators in micro fluidic channels
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Impact of flow-through regime on the cultivation of epithelial cells on quartz crystal resonators in micro fluidic channels Impact of flow-through regime on the cultivation of epithelial cells on quartz crystal resonators in micro fluidic channels](/preview/png/239733.png)
چکیده انگلیسی
In this contribution the impact of culture medium flow on the cultivation of Madin-Darby canine kidney cells on quartz crystal resonators (QCRs) was studied. Cells were cultivated at different medium flow rates in a bioreactor chip containing 4 QCRs. Confluency and motility of cells were analyzed based on light microscopical pictures and impedance spectra of the resonators. Results were compared with cells cultivated in culture flasks mounted on a shaker and CFD simulation results of the bioreactor chip. Based on our studies the flow-regime in the micro fluidic channel geometry has major impact e.g. on the cell division rate.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Procedia Chemistry - Volume 1, Issue 1, September 2009, Pages 365-368
Journal: Procedia Chemistry - Volume 1, Issue 1, September 2009, Pages 365-368