کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
239771 | 466228 | 2012 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparison of Cytotoxic Changes in ECV304 Cell Through Exposure to DMSO and Sodium Butyrate Using Impedance Spectroscopy
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Comparison of Cytotoxic Changes in ECV304 Cell Through Exposure to DMSO and Sodium Butyrate Using Impedance Spectroscopy Comparison of Cytotoxic Changes in ECV304 Cell Through Exposure to DMSO and Sodium Butyrate Using Impedance Spectroscopy](/preview/png/239771.png)
چکیده انگلیسی
This paper decides an impedance spectroscopy measurement system for real-time monitoring of cellular toxicity. The system is used to compare the impedance response of ECV304 cells to two toxicants, dimethyl sulphoxide (DMSO) and sodium butyrate. The responses at different concentration of toxicants were plotted in 3-D impedance spectra and their correlation coefficients were calculated at four time points. Additionally, Phase contrast microscopy images were used to observe the effect of the two toxicants on the morphology change of the cells. The characteristic information of the spectra compared well with the morphological changes of cells, illustrating that the method is useful for monitoring cytotoxicity effects and cell viability.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Procedia Chemistry - Volume 6, 2012, Pages 89-99
Journal: Procedia Chemistry - Volume 6, 2012, Pages 89-99