Effect of Accelerated Stability Test on Characteristics of Emulsion Systems with Chitosan as a Stabilizer

Chitosan has been used as a stabilizer in the preparation of emulsion systems with Squalene as an oil phase, then Tween 80 and Span 85 as a surfactant. Water phase, oil phase and chitosan as a stabilizer stirred with a homogenizer speed of 15,000 rpm for 30 minutes. The results of accelerated stability test with extreme temperatures of 4̊C and 40̊C showed significant changes in viscosity, density and degree of stability. However, the degree of acidity was relatively still same in which closer to normal pH (6.3-6.4). The particle size analysis showed the size around 3 micrometers. This emulsion system can be applied as the media of active compound delivery, for example is the emulsion system of topical and oral preparation to overcome cellulite problem.