Potentially Antihyperglycemic from Biomass and Phycocyanin of Spirulina Fusiformis Voronikhin by in Vivo Test

Spirulina is one of the microalgae containing nutrients used as functional food and in theraupetic (active compound). Bioactive compound in Spirulina has antihyperglycemic activity or antidiabetes activity. Diabetes mellitus is a major health problem in the world. The research about the potential of microalgae as antihyperglicemic is important to do. The cultivation of microalgae was conducted in laboratory using flask and aquarium completed with non-stop aeration. Measurement of the antihyperglycemic activity in-vivo using mices that were fed with biomass containing Spirulina fusiformis Voronikhin and phycocyanin. Blood glucose levels were measured by methods of oral glucose tolerance test after a fasting period of 18 h. Oral administration of biomass and phycocyanin of Spirulina fusiformis V. at 0.15 mg · g–1 and 0.30 mg · g–1 proved to decrease the blood glucose level.