Investigation of Coenzyme Q10 by Voltammetry

A simple, accurate and rapid voltammetric method has been developed for the quantitative determination of coenzyme Q10. Studies with direct current voltammetry were carried out using a glassy carbon electrode (GCE) in a phosphate buffer solution (pH 6.86). A well-defined oxidation peak of CoQ10 was obtained at -0.600 V vs Ag/AgCl. The magnitude of the oxidation peak current has been found to be related to the concentration of the coenzyme over the range of (2.010-5 to 2.010-4 M) (r = 0,991). Antioxidant activity of CoQ10 was investigated.