Study of cell membrane based coatings in capillary electrochromatography

Neuronal cell line based membrane models were studied as capillary coatings by capillary electrochromatography. The membrane models were based either on membrane suspensions or on membrane lipid extractions. The stability of the coatings at different pH values and buffer compositions was studied. The results showed that the cell membrane suspension based coatings were stable over pH range of 6.5–10.8. The use of Hepes instead of TE buffer did not improve the coating performance.