Technological and probiotic selection criteria of a bile-adapted Bifidobacterium animalis subsp. lactis strain

The technological and probiotic properties of the bile-adapted strain Bifidobacterium animalis subsp. lactis 4549dOx have been studied in comparison with its parental strain IPLA4549. The survival of the bile-adapted derivative to the simulated gastrointestinal transit was significantly higher than that of the parental strain, except in the presence of 10% skimmed milk. The adherence of strain 4549dOx to the intestinal cell line HT29-MTX almost duplicated that of strain IPLA4549. However, both strains had similar behaviour throughout the shelf-life of fermented milk. In conclusion, the bile-adapted strain 4549dOx presented advantages for its inclusion in dairy probiotic foods.