کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2463086 1555100 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Feline immunodeficiency virus infection: A valuable model to study HIV-1 associated encephalitis
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Feline immunodeficiency virus infection: A valuable model to study HIV-1 associated encephalitis
چکیده انگلیسی

Feline immunodeficiency virus (FIV), like human immunodeficiency virus (HIV)-1, is a neurotropic lentivirus and is associated with neuropathology in natural and experimental infections. FIV enters the brain early following experimental infection, and virus has been proposed to enter the brain via the blood–brain barrier and blood–CSF barrier, within infected lymphocytes and monocytes/macrophages. However the entry of cell-free virus or the direct infection of brain endothelial cells and astrocytes of the blood–brain barrier may also contribute to CNS infection. This review explores the role played by the FIV model in the elucidation of mechanism of lentiviral entry to the brain and viral interactions with the CNS, particularly in relation to lymphotropic lentiviruses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Immunology and Immunopathology - Volume 123, Issues 1–2, 15 May 2008, Pages 134–137
نویسندگان
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