کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2463698 1555232 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Shedding of cephalosporin resistant Escherichia coli in pigs from conventional farms after early treatment with antimicrobials
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Shedding of cephalosporin resistant Escherichia coli in pigs from conventional farms after early treatment with antimicrobials
چکیده انگلیسی


• We evaluated if ceftiofur is a risk factor associated with emergence of CR E. coli.
• Occurrence of CR E. coli was extremely variable among farms.
• Pigs were more likely to be positive at slaughter if they were positive as piglets.
• Shedding of CR E. coli increased with the treatment and decreased with the age.
• CR positive sows were more likely to have positive offspring (P = 0.02).

This study assessed the dynamics of cephalosporin resistant (CR) E. coli populations during the life cycle of pigs treated early in life with ceftiofur or tulathromycin. The study was conducted at eight conventional pig farms; four for each treatment with ceftiofur or tulathromycin. At each farm, 70 7-day-old piglets were divided into two groups: a control group (n = 30) and a treatment group (n = 40). Faecal samples were collected on day 0 and on days 2, 7 and 180 post-treatment. Sows were also sampled on day 0. CR E. coli were selected on MacConkey agar with ceftriaxone.On five farms, 7-day-old piglets excreted CR E. coli before treatment associated with the presence of CR E. coli in sows. The occurrence of CR E. coli positive animals decreased with increasing piglet age. The remaining three farms tested negative for CR E. coli during the study period. Results demonstrated great variability in the frequency of CR E. coli positive animals between farms, independent of treatment. Treatment with ceftiofur resulted in a transitory increase in the counts of CR E. coli after 48 h. However, other risk factors including the presence of CR E. coli in sows and animal age were more important than antimicrobial treatment. Accordingly, intervention strategies targeting sows would likely have a beneficial effect in reducing the occurrence of antimicrobial resistance in primary pig production.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Veterinary Journal - Volume 211, May 2016, Pages 21–25
نویسندگان
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