کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2466047 | 1111849 | 2006 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Intravenous amiodarone treatment in horses with chronic atrial fibrillation Intravenous amiodarone treatment in horses with chronic atrial fibrillation](/preview/png/2466047.png)
Six horses without underlying cardiac disease were presented because of atrial fibrillation of between 5 and 12 months duration. These horses received an intravenous amiodarone treatment of 5 mg/kg/h for 1 h followed by 0.83 mg/kg/h for 23 h and subsequently 1.9 mg/kg/h for 30 h. During treatment, clinical signs were monitored and a surface ECG and an intra-atrial electrogram were recorded. Infusion was discontinued when sinus rhythm or side effects occurred. Four horses successfully cardioverted, of which one showed symptoms of hind limb weakness and weight shifting. Two horses did not cardiovert and showed similar side effects. In all horses, side effects disappeared within 6 h after termination of treatment. Cardiac side effects, such as pro-arrhythmia, were not seen in any of the horses. Total bilirubin slightly increased in three horses and normalised within four days. It was concluded that amiodarone has the potential to treat naturally occurring chronic atrial fibrillation in horses, although further research is needed to refine the infusion protocol.
Journal: The Veterinary Journal - Volume 172, Issue 1, July 2006, Pages 129–134