کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2478541 1113374 2007 19 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sucres et vaccins : du polysaccharide purifié au glycoconjugué semi-synthétique
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
Sucres et vaccins : du polysaccharide purifié au glycoconjugué semi-synthétique
چکیده انگلیسی
Over the last decades, capsular polysaccharides have been successfully used as antibacterial vaccines. Marketing several polysaccharide-protein conjugate vaccines filled the gap in many areas of children and infant vaccination. By facilitating access to structures of increasing complexity, recent progress in glycochemistry has enabled the design of more and more precisely defined glycoconjugate vaccines using synthetic saccharide components which mimic epitopes naturally implicated in protection. This strategy was recently validated in humans. It opens the way to new perspectives in vaccine research devoted to prophylactic and/or therapeutic applications against bacterial, fungal, parasitic or viral infections, and certain cancers.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annales Pharmaceutiques Françaises - Volume 65, Issue 1, January 2007, Pages 14-32
نویسندگان
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