کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2481267 1556235 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cimetidine: An anticancer drug?
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
Cimetidine: An anticancer drug?
چکیده انگلیسی

Cimetidine, H2 receptor antagonists, is commonly prescribed for gastric and duodenal ulcer disease. Additionally, cimetidine has been shown to have anticancer effects. This review describes the mechanism of antitumor action of cimetidine including its ability to interfere with tumor cell adhesion, angiogenesis and proliferation; its effect on the immune system; as well as inhibition of postoperative immunosuppression. Its anticancer effect is also compared to that of the other H2 receptor antagonists as well as outcomes of cimetidine in clinical studies in cancer patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmaceutical Sciences - Volume 42, Issue 5, 18 April 2011, Pages 439–444
نویسندگان
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