کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2483338 1114218 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Polymersomes for theranostics
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
Polymersomes for theranostics
چکیده انگلیسی

In spite of the clear potential of personalized medicine, its pace of implementation has not yet fulfilled initial hopes. Polymeric vesicles, also named polymersomes, are presented as versatile systems able to address issues of efficacy, specificity and controlled release of drugs in a wide range of pathological scenarios that might show the way to novel therapies. Extensive work has endowed these biomimetic structures with the ability to overcome the body's natural defences, remain stable for an extended time in circulation, tuneable membrane properties for controlled drug release, and the ability to be functionalized for active targeting and therefore reducing undesirable side effects. Additionally, this unique platform has the ability to integrate both drug delivery and medical imaging capabilities, widening the perspectives towards theranostics. Polymersomes hold promise for more effective treatments with both fewer side effects and superior outcomes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Drug Delivery Science and Technology - Volume 23, Issue 1, 2013, Pages 38-46