کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
2496193 1116113 2016 8 صفحه PDF سفارش دهید دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of supplementation with pomegranate juice on plasma C-reactive protein concentrations: A systematic review and meta-analysis of randomized controlled trials
ترجمه فارسی عنوان
اثر مکمل سازی با آب انار بر غلظت پروتئین پلاسما واکنشی C: بررسی سیستماتیک و متاآنالیز از کارآزمایی تصادفی شده شاهددار
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کلمات کلیدی
آب انار؛ عصاره انار؛ پروتئین پلاسما واکنشی C ؛ شاخص توده بدن؛ کاروتید ضخامت انتیما رسانه ای؛ فاصله اطمینان؛ متاآنالیز جامع ؛ پروتئین واکنشی C؛
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی بالینی
چکیده انگلیسی


• Pomegranate juice has a high content of antioxidants and bioactive polyphenols, being widely used for its antioxidant, anti-inflammatory and chemopreventive effects.
• The effect of pomegranate products supplementation was significant neither in experimental studies nor in some cross-over trials.
• The effect of pomegranate juice on C reactive protein levels was not significant.
• The impact of pomegranate juice on plasma C reactive protein levels of was independent of duration of supplementation.

BackgroundPomegranate juice (PJ) has a high content of antioxidants and bioactive polyphenols, being widely used for its antioxidant, anti-inflammatory and chemopreventive effects.PurposeThe objective of this meta-analysis consisted in investigating the impact of PJ on plasma C-reactive protein (CRP) concentrations.MethodsThe search included SCOPUS, Medline and two Iranian bibliographic databases namely MagIran and Scientific Information Database (from inception to December 09, 2014) to identify prospective trials for investigating the impact of pomegranate preparations on serum concentrations of CRP. Two independent reviewers extracted data on study characteristics, methods and outcomes.ResultsAmong 427 participants in the selected studies, 216 were allocated to PJ groups, and 211 to control group. Meta-analysis of data from 5 eligible randomized controlled trials (RCTs) arms did not provide compelling evidence as to a significant CRP-lowering effect of supplementation with pomegranate juice (WMD: −0.22 mg/l, 95% CI: −0.45, 0.01, p = 0.061). The impact of pomegranate juice on plasma CRP levels was found to be independent of duration of supplementation (slope: 0.003; 95% CI: −0.005, 0.011; p = 0.444).ConclusionIn conclusion, this meta-analysis of data from 5 prospective trials did not indicate a significant effect of PJ on plasma CRP levels, and this effect was independent of duration of supplementation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytomedicine - Volume 23, Issue 11, 15 October 2016, Pages 1095–1102
نویسندگان
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