کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2497568 1116210 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Anti-inflammatory activity of alkanoids and triterpenoids from Trichodesma amplexicaule Roth.
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی بالینی
پیش نمایش صفحه اول مقاله
Anti-inflammatory activity of alkanoids and triterpenoids from Trichodesma amplexicaule Roth.
چکیده انگلیسی

The phytochemical investigation of Trichodesma amplexicaule guided by bioassay, to isolation of triterpenoids and aliphatic phytoconstituents. To evaluate the anti-inflammatory activities of isolated phytoconstituents, models with carrageenan-induced acute arthritis and complete Freund's adjuvant (CFA)-induced chronic arthritis in rats were conducted. The investigated results showed that alkanoic acid significantly inhibited the carrageenan-induced acute arthritis. Moreover, alkane also supressed the development of chronic arthritis induced by CFA. It has been reported that alkane was the major phytoconstituent (1.03±0.00135%) in in vivo studies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytomedicine - Volume 13, Issue 3, 13 February 2006, Pages 152–156
نویسندگان
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