کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2497875 1116233 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی بالینی
پیش نمایش صفحه اول مقاله
Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds
چکیده انگلیسی

An ethanolic spissum extract of the aerial parts of Plantago lanceolata L. was examined for antispasmodic activity on isolated ileum and trachea of the guinea-pig. Isolated constituents were investigated as well. The P. lanceolata extract inhibited the contractions of the guinea-pig ileum that were induced by various agonists such as acetylcholine (ACh), histamine, potassium and barium ions. Additionally the trachea contractions induced by barium ions were inhibited. The compounds luteolin, acteoside, plantamajoside an catalpol peracetate but not catalpol, isoacteoside, lavandulifolioside and aucubin inhibited the ACh-induced contractions of the guinea-pig ileum. Luteolin and acteoside reduced the barium-induced contractions of the guinea-pig trachea. Two recently isolated compounds did not show antispasmodic activity: luteolin-3′,7-diglucuronide and β-hydroxy-acteoside.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytomedicine - Volume 14, Issue 6, 27 June 2007, Pages 409–415
نویسندگان
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