کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2509043 1117637 2006 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Consumption and costs of antihypertensive drugs in Mexico: Are diuretic agents a standing technological trajectory?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
Consumption and costs of antihypertensive drugs in Mexico: Are diuretic agents a standing technological trajectory?
چکیده انگلیسی

BackgroundLittle is known about hypertension medication consumption and costs in Mexico. Hypertension control is a pharmacological challenge and a public health issue.Objective(a) To compare drug sales, number of written prescriptions, and monthly treatment costs among 5 classes of antihypertensive drugs and (b) to analyze diuretic drug sales and prescriptions to determine whether these antihypertensive agents represent an established technological trajectory.MethodsA retrospective time series data study from 1999 to 2003.Data sources used were International Marketing Services of Mexico drug sales and the Mexico Prescription Audit databases. The 5 different classes of antihypertensive drugs were accommodated into 4 main technological trajectories according to their main biological mechanisms of action. Each technological trajectory was assessed using consumption and prescription data. Daily defined dose was used to calculate drug treatment costs.ResultsThe market for cardiovascular agents is one of the largest, and in 2003 accounted for a value market share of US $59 billion and a unit share of 40.7 million. Among cardiovascular agents, antihypertensive drugs made up a large percentage of market shares. Calcium channel blockers and angiotensin-converting enzyme inhibitors I had the biggest share value of the total cardiovascular market. Amlodipine had the highest share among calcium channel blockers, and enalapril and captopril had the largest share among angiotensin-converting enzyme inhibitors I. The top-selling diuretic drug was furosemide. The trend in number of prescriptions was parallel to that in sales. The diuretic spinorolactone was the most expensive drug treatment (US $59). Treatment with spinorolactone might represent 47% of the income of a Mexican family if their household income was close to minimum wage (US $124).ConclusionsThe most effective and least expensive drugs—diuretics—had the smallest market share of all antihypertensive agents in Mexico. Nevertheless, diuretic agents are still in use and kept over time a steady market share both in value and in units.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Social and Administrative Pharmacy - Volume 2, Issue 1, March 2006, Pages 22–37
نویسندگان
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