Chemical profiling of Jinqi Jiangtang tablets by HPLC-ESI-Q-TOF/MS

AimTo profile the chemical constituents in Jinqi Jiangtang tablets.MethodBased on the chromatographic retention behavior, fragmentation patterns of chemical components, and published literatures, a high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (HPLC-ESI-Q-TOF/MS) method was established to characterize and identify components in Jinqi Jiangtang tablets.ResultsA total of 52 chemical compounds, including eight iridoid glycosides, seven phenolic acids, twelve alkaloids, six flavonoids, and nineteen saponins, were identified in Jinqi Jiangtang tablets.ConclusionThe established method could serve as a powerful tool for structural characterization and quality control of this Chinese herbal preparation.