Five Lignans and an Iridoid from Sambucus williamsii

AimTo study the chemical constituents of the 60% ethanol extract of the stems of Sambucus williamsii Hance.MethodsCompounds were isolated and purified by macroporous adsorptive resin D101, silica gel, and ODS column chromatographies and preparative HPLC. Their structures were identified by spectroscopic methods.ResultsFive lignans and one iridoid were isolated from the stems of Sambucus williamsii Hance. and their structures were identified as dehydrodiconiferyl alcohol-4-O-β-D-glucopyranoside (1), dihydrodehydrodiconiferyl alcohol-4-O-β-D-glucopyranoside (2), (7S, 8R)-dihydro-3'-hydroxy- 8-hydroxy-methyl-7-(4-hydroxy-3-methoxy-phenyl)-1'-benzofuranpropanol (3), erythro-1-(4-hydroxy-3-methoxyphenyl)-2-[2-hydroxy-4-(3-hydroxypropyl) phenoxy]-1, 3-propanediol (4), threo-1-(4-hydroxy-3-methoxyphenyl)-2-[2-hydroxy-4-(3-hydroxypropyl) phenoxy]-1, 3-propanediol (5), and morroniside (6) with about 70% α-morroniside and 30% β-morroniside.ConclusionCompounds 1, 4 and 5 were isolated from this genus for the first time, and compounds 2, 3 and 6 were obtained from the plant for the first time.