Anthraquinone Glycosides from the Roots of Prismatomeris connata

AimTo study the anthraquinone glycosides and their cytotoxicity from the roots of Prismatomeris connata.MethodsThe chemical constituents were isolated by Diaion HP-20 resin, silica gel, Sephadex LH-20 and ODS column chromatography and the structures were elucidated on the basis of spectral analysis. The cytotoxic activity was evaluated by MTT method.ResultsSix known anthraquinone glycosides were obtained and their structures were identified as 1-O-methylrubiadin 3-O-β-primeveroside (1), damnacanthol 3-O-β-primeveroside (2), rubiadin 3-O-β-primerveroside (3), lucidin 3-O-β-primeveroside (4), 1, 3-dihydroxy-2-(methoxymethyl) anthraquinone 3-O-β-primerveroside (5), and digiferruginol ω-gentiobiose (6).ConclusionAll the compounds were isolated from this genus for the first time.