Five New ent-Kaurane Diterpenoids from Isodon pharicus

AimTo study the chemical constituents of the aerial parts of Isodon pharicus.MethodsSilica gel, C18 reversed phase silica gel and HPLC were used. The structures were elucidated by extensive spectroscopic methods (IR, UV, MS and NMR).ResultsFive ent-kaurane diterpenoids, pharicunins N–R (1–5), were isolated and identified.ConclusionAll of the compounds are new.