Two New Terpenoids from Valeriana officinalis

AimTo study the chemical constituents of the roots of Valeriana officinalis L.MethodsChemical constituents were isolated by various column chromatographic techniques and their structures were elucidated by spectroscopic methods.ResultsA new sesquiterpene, orivalerianol (4β, 10α, 15-trihydroxy-aromadrendane) (1), and a new iridoid, monovalerianester A (aglycone of kanokoside A) (2) together with eight known compounds rulepidol (3), behenic acid (4), pinoresinol (5), valerenic acid (6), β-sitosterol (7), kanokoside A (8), prinsepiol-4-O-β-D-glucoside (9) and 8-hydroxypinoresinol-4-O-β-D-glucoside (10) were obtained from the EtOAc extract (1∼6) and n-BuOH extract (7∼10).ConclusionCompounds 1 and 2 are new natural products.