A new eudesmane sesquiterpenoid lactone from Chloranthus japonicus

AimTo study the chemical constituents of the whole plant of Chloranthus japonicus.MethodsCompounds were isolated and purified by column chromatography. Their structures were elucidated on the basis of spectroscopic methods.ResultsSix sesquiterpenoids were obtained and their structures were identified as chlojaponilactone A (1), atractylenolide III (2), neolitacumone B (3), 10α-hydroxy-1-oxoeremophila-7(11), 8(9)-diene-8, 12-olide (4), shizukanolide C (5), and shizukanolide H (6).ConclusionCompound 1 is a new eudesmane-type sesquiterpenoid lactone, and compounds 3 and 4 have been isolated from this species for the first time.