کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2526889 | 1558049 | 2012 | 4 صفحه PDF | دانلود رایگان |
AimTo study the chemical constituents and their bioactivity of Polygonum amplexicaule.MethodsThe isolation of compounds was achieved by chromatographic techniques and structure of the isolates was established by UV, IR, HRESI-MS and NMR including 1D and 2D experiments.ResultsBioassay-guided fractionation of an ethanolic extract of Polygonum amplexicaule led to the isolation of a hitherto unidentified compound, 5, 6-dihydropyranobenzopyrone (1) along with nine previously known compounds (2–10). Compounds 2–10 were identified as amplexicine (2), catechin (3), rutin (4), quercetin-3-O-β-D-galactopyranoside (5), chlorogenic acid (6), galloyl glucose (7), caffeic acid (8), gallic acid (9) and scopletin (10).ConclusionCompound 1 is new. Compounds 1–10 exhibited considerable antioxidant activity in a 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay.
Journal: Chinese Journal of Natural Medicines - Volume 10, Issue 1, January 2012, Pages 28-31