Two Furostanol Saponins from the Fruits of Tribulus terrestris

ABSTRACTAIMTo study the furostanol saponins from the fruits of Tribulus terrestris.METHODSThe constituents from T. terrestris were separated and purified by silica gel chromatography, reversed-phase silica gel chromatography and RP-HPLC. Their structures were elucidated on the basis of chemical evidence, spectral data and chemical reactions.RESULTSTwo furostanol saponin were identified as 3-O-{β-D-xylopyranosyl(1→3)-[β-D-xylopyranosyl(1→2)]-β-D-glucopyranosyl (1→4)-[α-L-rhamnopyranosyl (1→2)]-β-D-galactopyranosy}-26-O-β-D-glucopyranosyl-5α-furost-12-one-22-methoxyl-3β,26-diol(named terrestroside A) and 3-O-{β-D-xylopyranosyl(1→3)-[β-D-xylopyranosyl(1→2)]-β-D-glucopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-galactopyranosy}-26-O-β-D-glucopyranosyl-5a-furost-22-methoxyl-3β,26-diol.CONCLUSIONTerrestroside A is a new furostanol saponin.