Simultaneous Determination of 26 Pesticide Residues in 5 Chinese Medicinal Materials Using Solid-phase Extraction and GC-ECD Method

AimTo develop an analytical method for the simultaneous determination of 26 pesticide residues including 21 organochlorines and 5 pyrethroids in 5 crude Chinese medicinal materials by gas chromatography-electron capture detector (GC-ECD) method.MethodsFlorisil solid-phase extraction (SPE) was used for the clean-up of samples and GC-ECD for the determination. The separation of the target pesticides was carried out on HP-5 quartz capillary column in an optimized oven program with nitrogen as a carrier at a constant flow of 1.0 mL·min−1and the injection inlet valve was set at 260 °C and ECD at 330 °C.ResultsThe florisil solid-phase extraction was effective for the clean-up of the samples. For 26 pesticides, LODs and LOQs of the developed method were 0.386–2.500 ng·g−1 and 0.879–6.250 ng·g−1, respectively, and the average recoveries were found to be 69.61%–112.80% (RSD = 2.43%–15.18%, n = 9).ConclusionThe developed method can be used to simultaneously determine the 26 pesticide residues in 5 Chinese medicinal materials, and it is potential for the determination of other similar Chinese medicinal materials.