کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2527308 | 1119908 | 2012 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Efficacy and Tolerability of Fimasartan, a New Angiotensin Receptor Blocker, Compared With Losartan (50/100 mg): A 12-Week, Phase III, Multicenter, Prospective, Randomized, Double-Blind, Parallel-Group, Dose Escalation Clinical Trial With an Optional 12-W
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In this study with eligible adult Korean patients who had mild-to-moderate hypertension, the reduction of siDBP after 12 weeks of treatment with fimasartan 60/120 mg was noninferior to that of losartan 50/100 mg. By post hoc comparison, between-group differences in siDBP were significant in favor of fimasartan, suggesting superiority to losartan. There was no statistically significant difference in tolerability between the groups. This efficacy and tolerability were maintained throughout the additional 12-week extension study. ClinicalTrials.gov identifier: NCT00922480.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Therapeutics - Volume 34, Issue 3, March 2012, Pages 552-568.e9
Journal: Clinical Therapeutics - Volume 34, Issue 3, March 2012, Pages 552-568.e9
نویسندگان
Sang Eun MD, Yong-Jin MD, Hae-Young MD, Han-Mo MD, Chang-Gyu MD, Jae-Joong MD, Soon-Kil MD, Moo-Yong MD, Byung-Hee MD, PhD, Investigators Investigators,