کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2535053 1559105 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of 17α-ethinyl estradiol on active phase rapid eye movement sleep microarchitecture
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
Effect of 17α-ethinyl estradiol on active phase rapid eye movement sleep microarchitecture
چکیده انگلیسی

Estrogen treatment decreases active phase rapid eye movement (REM) sleep in ovariectomized rats. Here we explored further the effect of 17α-ethinyl estradiol (17α-EE) on active phase REM sleep in ovariectomized rats by analyzing spectral properties and the number and length of REM sleep bouts. The greatest suppression of REM sleep occurred on day 4 of 17α-EE treatment, was due to decreases in bout length, and was accompanied by decreased EEG theta power. These results further elucidate 17α-EE's effects on REM sleep and provide greater understanding of the mechanisms by which estrogens alter sleep–wakefulness patterns.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmacology - Volume 591, Issues 1–3, 4 September 2008, Pages 315–318
نویسندگان
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