کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2535389 | 1559114 | 2008 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Corticotropin releasing factor in the median raphe nucleus is involved in the retrieval of fear memory in rats
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Corticotropin releasing factor in the median raphe nucleus is involved in the retrieval of fear memory in rats Corticotropin releasing factor in the median raphe nucleus is involved in the retrieval of fear memory in rats](/preview/png/2535389.png)
چکیده انگلیسی
In the present study, we examined the role of corticotropin releasing factor (CRF) in the median raphe nucleus (MRN) on fear-related behaviors in rats. We employed the contextual fear conditioning test and the elevated plus maze test as memory-dependent and -independent tasks, respectively. Human/rat CRF (10 ng) in 0.5 μl saline was injected into the MRN. Administration of CRF significantly increased memory dependent, but not independent, fear expression. These results suggest that CRF release in the MRN is involved in the retrieval of fear memory.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Pharmacology - Volume 584, Issues 2–3, 28 April 2008, Pages 357–360
Journal: European Journal of Pharmacology - Volume 584, Issues 2–3, 28 April 2008, Pages 357–360
نویسندگان
Yu Ohmura, Taku Yamaguchi, Takeshi Izumi, Machiko Matsumoto, Mitsuhiro Yoshioka,