کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2538126 | 1559634 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Terpenoids with anti-inflammatory activity from Abies chensiensis
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
The phytochemical investigation of Abies chensiensis led to the isolation and identification of nine new compounds including eight triterpenoids (1–8) and a new abietane-type diterpene (9), along with three known compounds (10 − 12). The absolute configuration of 9 was assigned by X-ray diffraction analysis. Compounds 1–11 were evaluated for the anti-inflammatory activity. Among the tested compounds, 1, 2, 5 and 6 exhibited potent inhibitory activity with IC50 values of 15.97, 18.73, 20.18 and 10.97 μM, respectively.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 111, June 2016, Pages 87–94
Journal: Fitoterapia - Volume 111, June 2016, Pages 87–94
نویسندگان
Qian-Qian Zhao, Shu-Fang Wang, Ya Li, Qiu-Yan Song, Kun Gao,