Five new cycloartane triterpenoids from Beesia calthifolia

Phytochemical study on rhizomes of Beesia calthifolia resulted in the isolation of five new (1–5) and three known (6–8) cycloartane triterpenoids possessing a hemiketal or ketal group at C-24 from the EtOAc fraction of 95% ethanol extract. Their structures were determined by spectroscopic and chemical methods, especially HRMS and 2D NMR techniques. Compounds 3 and 4 showed potential hepatoprotective activities against d-galactosamine induced human hepatic L02 cell damage.

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