کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2538510 1559647 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New amino butenolides from the bulbs of Fritillaria unibracteata
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
New amino butenolides from the bulbs of Fritillaria unibracteata
چکیده انگلیسی

Five new amino γ-butenolides, fritenolide A (1), B (2), C (3), D (4), and E (5), along with four known compounds, were isolated from the bulbs of Fritillaria unibracteata. Their structures were determined by spectroscopic analysis, including 1D NMR, 2D NMR, HRESIMS, HRESIMS/MS, IR, and CD techniques. All isolates were evaluated for the protective activity on injured hepatocytes and cytotoxic activity on human cancer cells in vitro. The unusual amino butenolides were isolated from the Liliaceae family for the first time.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 98, October 2014, Pages 53–58
نویسندگان
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