کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2538610 | 1559653 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
New furoquinoline alkaloids from the leaves of Evodia lepta
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Three new furoquinoline alkaloids, leptanoines A–C (1–3) along with three known compounds (4–6) were isolated from the leaves of Evodia lepta. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities. Compound 4 showed the highest inhibitory activity towards BChE with an IC50 value of 47.9 μM. On the other hand, Compound 5 showed the highest inhibitory activity towards AChE with an IC50 value of 69.1 μM.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 92, January 2014, Pages 270–273
Journal: Fitoterapia - Volume 92, January 2014, Pages 270–273
نویسندگان
Jirapast Sichaem, Apapond Jirasirichote, Krittakorn Sapasuntikul, Suttira Khumkratok, Pattara Sawasdee, Thi My Lien Do, Santi Tip-pyang,