کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2538922 | 1122159 | 2011 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: A new coumestan with immunosuppressive activities from Flemingia philippinensis A new coumestan with immunosuppressive activities from Flemingia philippinensis](/preview/png/2538922.png)
A new coumestan, 1,3,9-trihydroxy-8-methoxycoumestan, named flemicoumestan A 1 together with nine isoflavone-related compounds were isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. Their structures were elucidated and confirmed by spectroscopic methods and literature data. Compounds 3 and 4 showed strong lymphocyte proliferation inhibitory activity with an IC50 value of 1.04–2.76 μM, and the low cytotoxicity with the CC50 value of 71.01 and 56.36 μM, respectively.
A novel coumestan, flemicoumestan A (1), together with nine known compounds, was isolated from the ethyl acetate extract of the roots of Flemingia philippinensis. The structures were determined by spectroscopic methods. All the compounds were evaluated for their immunosuppressive activities in vitro.Figure optionsDownload as PowerPoint slide
Journal: Fitoterapia - Volume 82, Issue 4, June 2011, Pages 615–619