کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2538929 1122159 2011 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Anti-inflammatory, antioxidant and antifungal furanosesquiterpenoids isolated from Commiphora erythraea (Ehrenb.) Engl. resin
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Anti-inflammatory, antioxidant and antifungal furanosesquiterpenoids isolated from Commiphora erythraea (Ehrenb.) Engl. resin
چکیده انگلیسی

The topical anti-inflammatory, free radical scavenging and antifungal activities of essential oils and extracts of Commiphora erythraea (Ehrenb.) Engl. resin were investigated. The hexane extract significantly inhibited oedema when applied topically in Croton oil-induced ear oedema assay in mice. The same extract showed antioxidant activity in DPPH radical scavenging assay. A bioguided separation of the hexane extract led to the isolation of furanosesquiterpenoids 1 and 2 that showed a weak antifungal activity, while compounds 3–5 resulted to be antioxidant (EC50 4.28, 2.56 and 1.08 mg/mL, respectively) and anti-inflammatory (30, 26 and 32% oedema reduction, respectively).

From the hexane extract of Commiphora erythraea resin five furanosesquiterpenoids were isolated. Compounds 1 and 2 showed an antifungal activity, while compounds 3–5 resulted to be antioxidant and anti-inflammatory.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 82, Issue 4, June 2011, Pages 654–661
نویسندگان
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