Blumeaxanthene II, a novel xanthene from Blumea riparia DC

A novel xanthene (1), blumeaxanthene II, was isolated from the aerial parts of Blumea riparia (Bl.) DC., a Chinese medicinal plant with hemostatic properties, and its structure was determined by extensive spectroscopic analyses. This compound is the first example of a halogenated xanthene from a natural plant, and a biosynthetic pathway was proposed. Blumeaxanthene II was also tested against Bel-7404 cells in vitro but was found to be only weakly cytotoxic.

One new compound blumeaxanthene II (1) and nine known compounds were isolated from Blumea riparia DC. Their structures were determined by analysis of spectroscopic data.Figure optionsDownload as PowerPoint slide