کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2539068 | 1122163 | 2010 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Immunomodulatory activity in vitro and in vivo of polysaccharide from Potentilla anserina Immunomodulatory activity in vitro and in vivo of polysaccharide from Potentilla anserina](/preview/png/2539068.png)
The polysaccharide (PAP) from Potentilla anserina was evaluated for modulating effects by using mouse peritoneal macrophage and the immunosuppressed-model cyclophosphamide-induced. Phagocytotic and mononuclear phagocytic system function assays showed that PAP stimulated the phagocytosis of phagocyte. Splenocyte proliferation assay showed that PAP acted the effect combining Con A or LPS in splenocyte proliferation. The parameters detected showed that PAP increased thymus and spleen indices, the levels of LDH and ACP in the spleen, and IL-10and IFN-γ in serum in immunosuppressed mice. The results suggest that PAP is involved in immunomodulatory effects leading to the exploration for PAP as a potential immunostimulant.
The polysaccharide from Potentilla anserina showed synergistic stimulation effect in immunosuppressed mice is involved in immunomodulatory effects leading to the exploration for the polysaccharide as a potential immunostimulant.Figure optionsDownload as PowerPoint slide
Journal: Fitoterapia - Volume 81, Issue 8, December 2010, Pages 1117–1124