کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2539068 1122163 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunomodulatory activity in vitro and in vivo of polysaccharide from Potentilla anserina
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی داروشناسی
پیش نمایش صفحه اول مقاله
Immunomodulatory activity in vitro and in vivo of polysaccharide from Potentilla anserina
چکیده انگلیسی

The polysaccharide (PAP) from Potentilla anserina was evaluated for modulating effects by using mouse peritoneal macrophage and the immunosuppressed-model cyclophosphamide-induced. Phagocytotic and mononuclear phagocytic system function assays showed that PAP stimulated the phagocytosis of phagocyte. Splenocyte proliferation assay showed that PAP acted the effect combining Con A or LPS in splenocyte proliferation. The parameters detected showed that PAP increased thymus and spleen indices, the levels of LDH and ACP in the spleen, and IL-10and IFN-γ in serum in immunosuppressed mice. The results suggest that PAP is involved in immunomodulatory effects leading to the exploration for PAP as a potential immunostimulant.

The polysaccharide from Potentilla anserina showed synergistic stimulation effect in immunosuppressed mice is involved in immunomodulatory effects leading to the exploration for the polysaccharide as a potential immunostimulant.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 81, Issue 8, December 2010, Pages 1117–1124
نویسندگان
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