Isolation and identification of the antibacterial active compound from petroleum ether extract of neem oil

From a petroleum ether extract of neem oil (Azadirachta indica A. Juss) the new tetrahydrofuranyl diester 1 was isolated as an anti-bacterial constituent. 1 showed significant activities against three standard bacterial strains, including Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 and Salmonella enteritidis CMCC (B) 50041.

M-Octadecanoic acid-3,4-Tetrahydrofuran Diester, isolated from the petroleum ether extract of neem oil, showed potent antibacterial activity.Figure optionsDownload as PowerPoint slide